How Old is Too Old? Expanding Living Kidney Organ Transplantation from Donors above 60 Years of Age with Associated Comorbidity.
Transplant Surgery, St Georges University Hospital NHS Foundation Trust, London, United Kingdom.
Meeting: 2018 American Transplant Congress
Abstract number: C143
Keywords: Donation, Kidney transplantation
Session Information
Session Name: Poster Session C: Kidney Living Donor Issues
Session Type: Poster Session
Date: Monday, June 4, 2018
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall 4EF
Background: Worldwide the population is ageing. In UK there are more people above 60 than under 16 years of age. Hence there are more elderly people coming forward as potential living organ donors. For kidney donation age on its own has never been an absolute contraindication but increasing age and associated co-morbidities can potentially increase risks to donor's health and life. In this study we aimed to analyse outcome of donors above and below 60-years-of-age with associated hypertension.
Methods: We performed a retrospective analysis of outcome of living kidney donors from 1997 to 2016 performed in our unit. We compared the outcome among above and below 60. We used SPSS software for statistical analysis.
Results:
| Demographics and outcomes | Cohort A < 60 with HTN (n=39) | Cohort B > 60 with HTN (n=21) | Significance |
| Gender: Female (%) | 51% | 60% | 0.210 |
| Age in years (median:range) | 45.5 (18-59) | 63 (60-76) | <0.01 |
| BMI (kg/m2) (median:range) | 26 (17.7-38) | 26 (18-35) | 0.480 |
| GFR combined pre-donation (median:range) | 94 (70-148) | 86 (63.8-119) | <0.01 |
| GFR of donor post nephrectomy discharge (median:range) | 51 (34.5-74) | 48 (33.2-74) | <0.01 |
| GFR of donor post nephrectomy 12 months(median:range) | 55 (38-148) | 47 (33.2-119) | <0.01 |
| Haemorrhage | 2 | 1 | 0.484 |
| Chest infection | 4 | 8 | <0.01 |
| Wound infection | 2 | 2 | 0.241 |
| UTI | 4 | 4 | 0.523 |
| VTE | 1 | 1 | <0.01 |
| Open conversion | 1 | 0 | <0.01 |
| Median hospital stay | 3 | 4.5 | <0.01 |
Conclusion: With proper pre-donation workup and consenting, organ donation among elderly donors above 60 with controlled hypertension is a safe option.
CITATION INFORMATION: Ghazanfar A., Salih L. How Old is Too Old? Expanding Living Kidney Organ Transplantation from Donors above 60 Years of Age with Associated Comorbidity. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Ghazanfar A, Salih L. How Old is Too Old? Expanding Living Kidney Organ Transplantation from Donors above 60 Years of Age with Associated Comorbidity. [abstract]. https://atcmeetingabstracts.com/abstract/how-old-is-too-old-expanding-living-kidney-organ-transplantation-from-donors-above-60-years-of-age-with-associated-comorbidity/. Accessed November 23, 2024.« Back to 2018 American Transplant Congress