Introduction: Accurate estimation of split renal function in living kidney donors is important for side-selection and a sufficient long-term residual renal function. The present study was conducted to analyze the need of radioisotope renography in the assessment of split renal function in potential living kidney donors.

Methods: This prospective study included 25 patients who underwent live donor nephrectomy between January and May 2015. All donors underwent diethylenetriamine pentaacetic acid (DTPA) renal scans and computerized tomography angiography. Then bilateral renal cortex volume was estimated base on the reconstructed 3D CT images. Correlation and agreement of methods were analyzed using Spearman's rho correlation coefficient and association with remnant renal function was demonstrated.

Results: The mean preoperative eGFR was 101.3 ml/minute/1.73 m², and GFR estimated DTPA was 92.6 ml/minute/1.73 m². The mean CT-volumetry was 341.9 cm². There was good correlation between two methods predicting total renal function. However, there were clinically relevant differences in split renal function in 5/25 subjects (20 %). Predicting dominating side was not agreed in 11/25 (44%) subjects. Neither DTPA nor CT-volumetry predicts remnant renal function at 3 month postoperatively.

Conclusion: The CT-volumetry was correlated with DTPA renal scan. However, neither DTPA nor CT-volumetry predicts remnant renal function after kidney donation.

CITATION INFORMATION: Yoon Y, Lee H, Joo D, Huh K, Kim M, Kim S, Kim Y, Han W. Do We Need Radioisotope Renography in Evaluation of Split Renal Function in Living Kidney Donors? Am J Transplant. 2016;16 (suppl 3).

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