2020 American Transplant Congress
The 1st Year Posttransplant Course Reliably Predicts Kidney Graft Survival up to 15 Years Using a Machine Learning-Based Modeling Approach
Hannover Medical School, Hannover, Germany
*Purpose: Identification of patients at risk for graft failure can improve individual surveillance and early therapeutic interventions. We used a well-documented patient cohort to establish…2019 American Transplant Congress
C1q Dominant Deposits in Renal Transplant Biopsies Are Not Associated with Allograft Dysfunction
*Purpose: Complement deposition in renal allograft biopsies and native kidneys may represent an ongoing inflammatory process. We studied the significance of incidental finding of predominant…2019 American Transplant Congress
Clinical Features of IgA Nephropathy Recurrence after Kidney Transplantation
*Purpose: Recurrence of IgA nephropathy (IgAN) is one of the major cause of kidney graft loss. The clinical features of disease recurrence after kidney transplantation…2019 American Transplant Congress
Mesangiopathic Glomerulonephritis in Kidney Transplants
*Purpose: Describe higher than anticipated prevalence of Mesangiopathic Glomerulonephritis on surveillance biopsies.*Methods: Review of all surveillance biopsies from September 2014 through September 2018 for presence…2019 American Transplant Congress
When to Hold: Apixaban in Renal Transplant Recipients
1Yale New Haven Hospital, New Haven, CT, 2Yale School of Medicine, New Haven, CT
*Purpose: Renal transplant recipients (RTRs) may develop deep venous thrombosis (DVT), pulmonary embolism (PE), or atrial fibrillation requiring treatment with oral anticoagulation. There is limited…2019 American Transplant Congress
Impact of Six-Month Surveillance Biopsies and Monitoring on 2-Year Outcomes in Pediatric Renal Transplant Recipients
*Purpose: Evaluate the utility of surveillance biopsies on post-transplant outcomes.*Methods: A retrospective single center chart review of pediatric renal transplant recipients from 01/2011-10/2015 was conducted.…2019 American Transplant Congress
Effect of Race and Antibody-Mediated Injury on Outcomes after Early Subclinical Inflammation
University of Alabama, Birmingham, AL
*Purpose: The impact of subclinical inflammation (SCI) on transplant outcomes has been variable, based on previous studies in homogeneous cohorts with relatively low immunologic risk.…2019 American Transplant Congress
Recurrent Diabetic Nephropathy Despite Intensive Glycemic Control: An Observational Cohort Study
*Purpose: After kidney transplantation, recurrence of diabetic nephropathy has been reported. The presentation and kinetics of recurrent diabetic nephropathy and its risk factors remain however…2019 American Transplant Congress
Humoral Immune Responses to Kidney Associated Non-HLA Antigens is Not Associated with Progression to Chronic Immune Injury in Kidney Transplant Recipients
1Mayo Clinic, Phoenix, AZ, 2St. Joseph’s Hospital, Phoenix, AZ
*Purpose: Development of donor specific anti-HLA (DSA) although is a known risk factor for Chronic immune injury (CII), it is undetectable in many patients with…2019 American Transplant Congress
IL-6R Blockade with Tocilizumab Increases Tregs and Decreases Early Graft Inflammation in Kidney Transplant Recipients: Results of a Randomized Controlled Trial
*Purpose: IL-6, a proinflammatory cytokine and key regulator of Treg/Th17 balance, is strongly associated with renal graft rejection. We hypothesized that IL-6 blockade with tocilizumab…
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