2020 American Transplant Congress
Hypothermia Attenuates Renal Fibrosis after Renal Ischemia Reperfusion in Mice
*Purpose: Recently, acute kidney injury is a important cause of chronic kidney injury, characterized by glomerular sclerosis and tubular fibrosis. Hypothermia attenuates the acute kidney…2020 American Transplant Congress
Exosomes Released from Natural Killer Cells Activation of Immune Responses: Role in Chronic Lung Allograft Dysfunction
Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Recent studies demonstrated natural killer (NK) cells can induce cytotoxicity both by direct cytotoxic mechanisms and antibody (Ab) dependent cytotoxicity; however its role in…2020 American Transplant Congress
The Therapeutic Potential of Human Liver-Derived Stem Cells Transplantation in Carbon Tetrachloride-Induced Rat Liver Cirrhotic Model
*Purpose: Cirrhosis is a long-term consequence of chronic hepatic injury and there are no effective treatment methods. Mesenchymal stem cells (MSCs) have been reported to…2020 American Transplant Congress
Mass-Spectrometry Based Discovery of Tubular Injury Marker in Chronic Kidney Disease
*Purpose: Renal tubular injury and interstitial fibrosis are inevitable processes in the progression of chronic kidney disease (CKD). The purpose of this study is to…2020 American Transplant Congress
Regulatory T Cell-Derived Amphiregulin Activates Fibroblasts to Promote Chronic Rejection after Heart Transplantation
*Purpose: Chronic rejection (CR) after organ transplantation (Tx) manifests as function-limiting allograft fibrosis and vasculopathy. Current immunosuppressants fail to prevent CR and insights into the…2020 American Transplant Congress
Characterization of Gut Microbiome in Liver Transplant Recipients with Non-Alcoholic Steatohepatitis
*Purpose: Non-alcoholic fatty liver disease (NAFLD) and its progressive form non-alcoholic steatohepatitis (NASH) is a growing problem globally and recurs even after liver transplant (LT).…2020 American Transplant Congress
Graphene Quantum Dots Prevent Glomerular and Interstitial Injury in Murine Adriamycin Nephropathy Through Macrophage Depletion
*Purpose: Macrophage infilatration is a key feature of the pathogenicity associated with glomerular and tubulo-interstitial injury in kidney disease. Graphene quantum dots (GQDs) are considered…2020 American Transplant Congress
Fibrosing Cholestatic Hepatatitis in Post Renal Transplant and Successful Treatment with Newer DAA Therapy
Nephrology, Manipal Hospital, Bangalore, India
*Purpose: Fibrosing cholestatic hepatitis is often fatal post renal transplantation. we report a case of successful treatment of FCH and complete recovery*Methods: A 53 year…2020 American Transplant Congress
Molecular Phenotypes of Liver Transplant Injury: The INTERLIVER Study
1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2., ., AB, Canada
*Purpose: Liver parenchymal injury phenotypes are difficult to evaluate by histology but could be amenable to molecular assessment. Having developed a Molecular Microscope® Diagnostic System…2020 American Transplant Congress
Persistent Fibrinolysis Shutdown in Liver Transplant Recipients is Associated with Early Allograph Dysfunction
*Purpose: Early allograph dysfunction (EAD) in liver transplantation has been attributed to microvascular thrombosis. Treating grafts at risk of EAD with tissue plasminogen activator (tPA)…
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